CompositionMethylcobalamin (500 mcg)
SALT INFORMATIONMethylcobalamin (500 mcg) TYPICAL USAGE peripheral neuropathy, megaloblastic anaemia SIDE EFFECTS Anorexia, nausea, vomiting and diarrhoea. DRUG INTERACTION Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. MECHANISM OF ACTION Mecobalamin is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.