CompositionBenzyl Nicotinate (0.2%w/v),Vitamin K (0.1%w/v)
SALT INFORMATIONBenzyl Nicotinate (0.2%w/v) TYPICAL USAGE Skin ulcers, thrombophlebitis, haematomas, superficial thrombosis SIDE EFFECTS Nausea, stomach upset, skin rash, acute toxicity. DRUG INTERACTION Tell your doctor of all prescription and nonprescription medication you may use. Do not start or stop any medicine without doctor or pharmacist approval. MECHANISM OF ACTION Heparin-Benzyl Nicotinate Ointment is used to treat and prevent blood clots. Vitamin K (0.1%w/v) TYPICAL USAGE Haemorrhage, over dosage of anticoagulants, vitamin deficiency. SIDE EFFECTS Bronchospasm, sweating, flushing, hematoma, chest tightness, anaphylactic reactions. DRUG INTERACTION Vitamin K is known to interact with other drugs like cholestyramine, colestipol (HCl), nicoumalone, oxytetracycline (Dihydrate), phenindione, phenobarbitone, phenytoin (Na), tocopherol (Vitamin E), warfarin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Vitamin K is an essential cofactor for the gamma-carboxylase enzymes which catalyze the posttranslational gamma-carboxylation of glutamic acid residues in inactive hepatic precursors of coagulation factors II (prothrombin), VII, IX and X. Gamma-carboxylation converts these inactive precursors into active coagulation factors which are secreted by hepatocytes into the blood.