CompositionProgesterone (200 mg)
SALT INFORMATIONProgesterone (200 mg) TYPICAL USAGE Recurrent miscarriage, amenorrhoea, abnormal uterine bleeding, palliative treatment of advanced, inoperable endometrial carcinoma SIDE EFFECTS GI disturbances, increased appetite, weight gain or loss, oedema, acne, allergic skin rashes, urticaria, mental depression, discomfort in breast, cough, dyspnoea. DRUG INTERACTION Hydroxyprogesterone caproate is known to interact with other drugs like carbamazepine, phenytoin, ciclosporin. MECHANISM OF ACTION Hydroxyprogesterone caproate stimulates luteal actions, changes in uterus and vagina as seen in early pregnancy. It also has prolonged uterotrophic effect. Contractile response of the myometrium to oxytocin is inhibited.