CompositionLevocetirizine Dihydrochloride (5mg),Montelukast (10mg) SALT INFORMATIONLevocetirizine Dihydrochloride (5mg) TYPICAL USAGE NSAID associated ulceration, to prevent recurrence of neural tube defect. SIDE EFFECTS Drowsiness, confusion, sleep disturbance, depression, bronchospasm, blood dyscrasias, convulsions, angioedema, liver dysfunction, incidence of sedation. DRUG INTERACTION Levocetrizine is known to interact with other drugs like alprazolam, diazepam, zolpidem, diphenhydramine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Levocetirizine is the active R enantiomer of cetirizine. It has an affinity for H1 receptors approximately 2-fold higher than racemic cetirizine and therefore strongly inhibits allergic (wheal and flare) reactions. Montelukast (10mg) TYPICAL USAGE Chronic asthma. Seasonal allergic rhinitis. Perennial allergic rhinitis. Prophylaxis of exercise-induced asthma. SIDE EFFECTS Angioedema, headache, restlessness, abdominal pain, agitation, oedema, allergy anaphylaxis. DRUG INTERACTION Montelukast is known to interact with other drugs like phenobarbital Sodium, prednisolone and prednisone, rifampicin. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.