CompositionTryptophan (100 mg) SALT INFORMATIONTryptophan (100 mg) TYPICAL USAGE Depression, insomnia, mania, nausea and vomiting (acute attacks), obesity, obsessive-compulsive disorders, pain, psychosis. SIDE EFFECTS Eosinophilia, myalgia, dizziness, headache, drowsiness, anorexia. DRUG INTERACTION Tryptophan is known to interact with other drugs like escitalopram, fluoxetine (HCl), isocarboxazid, paroxetine. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Kynurenine is the first key branch point intermediate in the pathway. Kynurenine undergoes deamniation in a standard transamination reaction yielding kynurenic acid. Kynurenic acid and metabolites have been shown to act as antiexcitotoxics and anticonvulsives. A second side branch reaction produces anthranilic acid plus alanine. Another equivalent of alanine is produced further along the main catabolic pathway, and it is the production of these alanine residues that allows tryptophan to be classified among the glucogenic and ketogenic amino acids.