CompositionAmitriptyline (25 mg)
SALT INFORMATIONAmitriptyline (25 mg) TYPICAL USAGE Depressive illness accompanied by anxiety, agitation, restlessness and disturbances of sleep. Masked depression, dysphoria and depression in alcoholics. SIDE EFFECTS Postural hypotension, tachycardia, cardiac arrhythmias, conduction disturbances, congestive heart failure, hypotension, cardiac arrhythmias, coma, seizures, blurred vision, dry mouth, urinary retention, hypothermia, metabolic acidosis, mydriasis, weakness, dizziness, headache, fatigue, constipation, dry mouth, blurred vision. DRUG INTERACTION Amitriptyline is known to interact with other drugs like adrenaline, alcohol, antazoline, apraclonidine (HCl), astemizole, bethanidine (Sulphate), bretylium (Tosylate), carbamazepine, cimetidine (HCl), cisapride, clonidine (HCl), debrisoquine (Sulphate), disopyramide, disulfiram, enflurane, ergotamine (Tartrate). MECHANISM OF ACTION Amitriptyline is a TCA that exerts its action by blocking neuronal re-uptake of noradrenaline and serotonin thus increasing synaptic concentration of serotonin and/or norepinephrine in the CNS.