CompositionPantoprazole (20 mg)
SALT INFORMATIONPantoprazole (20 mg) TYPICAL USAGE Duodenal ulcer. Gastric ulcer. Reflux oesophagitis. Prophylaxis of NSAID associated peptic ulcer. Zollinger-ellison syndrome and other hypersecretory states. SIDE EFFECTS Weakness, dizziness, nausea, vomiting, anxiety, dyspnea, pain, pharyngitis, cough, arthralgia, rhinitis, chest pain, bronchitis, backache, urinary frequency, UTI, hyperlipidemia. DRUG INTERACTION Pantoprazole is known to interact with other drugs like ampicillin, atazanavir, clarithromycin, clopidogrel, digoxin, ketoconazole, warfarin (Na). MECHANISM OF ACTION Pantoprazole is a proton pump inhibitor (PPI) that suppresses the final step in gastric acid production by forming a covalent bond to two sites of the (H+,K+ )- ATPase enzyme system at the secretory surface of the gastric parietal cell. This effect is dose- related and leads to inhibition of both basal and stimulated gastric acid secretion irrespective of the stimulus.