CompositionClonazepam (1 mg) SALT INFORMATIONClonazepam (1 mg) TYPICAL USAGE In treatment of typical and atypical absence infantile spasms, myoclonic epilepsy, atonic seizures, minor motor seizures of childhood, refractory grandmal epilepsy or temporal lobe epilepsy. SIDE EFFECTS Thrombocytopenia, blood dyscrasias, dizziness, drowsiness, fatigue, anorexia, tachycardia, sleep disturbances, rashes, vertigo, impotence, loss of libido, Somnolence, macular hypotonia, coordination disturbances, abnormal thirst, skin pigmentation. DRUG INTERACTION Clonazepam is known to interact with other drugs like alcohol, carbamazepine, iprindole, iproniazid phosphate, phenobarbitone, phenytoin (Na), valproic Acid. MECHANISM OF ACTION Allosteric interactions between central benzodiazepine receptors and gamma-aminobutyric acid (GABA) receptors potentiate the effects of GABA. As GABA is an inhibitory neurotransmitter, this results in increased inhibition of the ascending reticular activating system. Benzodiazepines, in this way, block the cortical and limbic arousal that occurs following stimulation of the reticular pathways.