Tablets and Capsules,Prescription Medicines

Atorva 80 Tab

Availablity: In stock

1 Strip(s) (10 Tablets each). This product is manufactured by CND (Zydus Cadila Healthcare Ltd)

₹ 370.00

Composition: “Atorvastatin Calcium 80mg”

Atorvastatin is in a group of drugs called “statins”. It is used primarily for lowering blood cholesterol and for preventing risks associated with cardiovascular disease.


Mechanism of action:

  • It acts by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.

Typical uses:

  • Primary uses of atorvastatin are dyslipidemia and cardiovascular disease. Help lower "bad" cholesterol and fats (such as LDL, triglycerides) and raise "good" cholesterol (HDL) in the blood.
  • Secondary uses are prevention of myocardial infarction, stroke, unstable angina.
    •                                                    

Contraindication:

  • Liver diseases like Cholestasis, Hepatic encephalopathy, Hepatitis and jaundice.
  • Pregnancy and Breastfeeding
  • Acute renal failure

Adverse Effects:

  • Myopathy with elevation of creatinine kinase (CK) and rhabdomyolysis are the major adverse effect.
    Diarrhea, Dyspepsia, Nausea, Arthralgia, Myalgia are the common adverse effect.

Drug interactions: 

  • Interactions with clofibrate, fenofibrate, gemfibrozil, used usually in combination with statins, increase the risk of myopathy and rhabdomyolysis.
  • Co-administration of atorvastatin with one of CYP3A4 inhibitors may increase serum concentrations of atorvastatin, which may lead to adverse reactions.
  • Niacin and colchicine is proved to increase the risk of myopathy or rhabdomyolysis
  • Vitamin D supplement lowers atorvastatin and active metabolite concentration.
  • Co-administration of grapefruit juice with atorvastatin may cause an increase in Cmax and AUC may lead to overdose toxicity. 

 

Product Specifications

Brand Zydus Cadila Healthcare Ltd