CompositionDocetaxel (80 mg)
SALT INFORMATIONDocetaxel (80 mg) TYPICAL USAGE Gastric cancer, Metastatic carcinoma of breast, Non-small cell lung carcinoma, Ovarian cancer, Pancreatic cancer, Squamous cell carcinoma, Squamous cell carcinoma of head. SIDE EFFECTS Neutropenia, Mild paresthesia, Cutaneous reactions, Asthenia. DRUG INTERACTION Information not available. MECHANISM OF ACTION Docetaxel disrupts the microtubular network in cells that is essential for vital mitotic and interphase cellular functions. It binds to the free tubulin and promotes the assembly of tubulin into stable microtubules while simultaneously inhibiting their disassembly, resulting in inhibition of mitosis.