CompositionCalcitonin (200 iu)
SALT INFORMATIONCalcitonin (200 iu) TYPICAL USAGE Treatment of post-menopausal osteoporosis, bone-loss from prolonged immobilization, advancing osteolytic hypercalcemia of malignancy, pain associated with metastatic bone cancer. Pagets disease. SIDE EFFECTS Anaphylactic reactions, transient vomiting, dizziness, headache, nausea, diarrhea, fever, rashes, itching, flushing. DRUG INTERACTION Calcitonin is known to interact with other drugs like pamidronate (disodium pentahydrate). These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Calcitonin binds to the calcitonin receptor (found primarily in osteoclasts) which then enhances the production of vitamin D producing enzymes (25-hydroxyvitamine D-24-hydroxylase), leading to greater calcium retention and enhanced bone density. Binding of calcitonin to its receptor also activates adenylyl cyclase and the phosphatidyl-inositol-calcium pathway.