CompositionOxymetazoline (0.25 mg)
SALT INFORMATIONOxymetazoline (0.25 mg) TYPICAL USAGE Nasal congestion. Conjunctival decongestant. SIDE EFFECTS Local stinging or burning, sneezing, dryness of mouth and throat. Prolonged or frequent use may cause rebound congestion. Headache, insomnia, tachycardia, hypertension, nervousness. DRUG INTERACTION Hypertensive crisis may occur with monoamine oxygenase Inhibitors. MECHANISM OF ACTION Oxymetazoline is a direct acting sympathomimetic amine, which acts on alpha-adrenergic receptors in the arterioles of the conjunctiva and nasal mucosa. It produces vasoconstriction, resulting in decreased conjunctival congestion in ophthalmic. In nasal it produces constriction, resulting in decreased blood flow and decreased nasal congestion.