Tablets and Capsules,Prescription Medicines

Numox 250mg Caps

Availablity: In stock

MRP:Rs. 66.80 for 1 Strip(s) (10 Capsule each). This product is manufactured by Jenburkt Pharmaceuticals Ltd

₹ 67.00

CompositionAmoxicillin (250mg),Cloxacillin (250mg) SALT INFORMATIONAmoxicillin (250mg) TYPICAL USAGE Respiratory, genito-urinary, skin and soft tissue, ENT infections due to susceptible strains of Gram negative organisms like H.influenzae, E-coli, P.mirabilis and N. gonorrhoea. SIDE EFFECTS Abscesses, acute bronchitis, bacteriuria, bronchitis, carbuncles, cellulitis, chronic bronchitis, cystitis, dental abscess, dental abscess (short-course), endocarditis, furunculosis, gonorrhoea, gynecological infections, haemophilus influenzae infections, dizziness, headache, anorexia, iarrhea, fever, abdominal pain, maculopapular rash, rashes, gastritis, indigestion, urticarial skin rash. DRUG INTERACTION Amoxicillin is known to interact with other drugs like chloramphenicol, methotrexate, probenecid, rabeprazole, sodium picosulphate, tetracycline (HCl), warfarin (Na). MECHANISM OF ACTION Amoxicillin binds to penicillin-binding protein 1A (PBP-1A) located inside the bacterial cell well. Penicillins acylate the penicillin-sensitive transpeptidase C-terminal domain by opening the lactam ring. This inactivation of the enzyme prevents the formation of a cross-link of two linear peptidoglycan strands, inhibiting the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that amoxicllin interferes with an autolysin inhibitor. Cloxacillin (250mg) TYPICAL USAGE Bacterial infections, bone and joint infection, cystitis, endocarditis, enterocolitis, meningitis associated with spina bifida, respiratory tract infections, septicaemia. SIDE EFFECTS Cholestatic jaundice, hemolytic anemia, blood dyscrasias, seizures, interstitial nephritis, vomiting, diarrhea, GI disturbances, skin reactions, rashes, phlebitis, glossitis, stomatitis. DRUG INTERACTION Cloxacillin is known to interact with other drugs like chloramphenicol, probenecid, tetracycline (HCl). These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, cloxacillin inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins; it is possible that cloxacillin interferes with an autolysin inhibitor.

Product Specifications

Brand Jenburkt Pharmaceuticals Ltd