CompositionPioglitazone (30 mg)
SALT INFORMATIONPioglitazone (30 mg) TYPICAL USAGE Diabetes mellitus type-II, softening and dilatation of cervix before mechanical cervical dilatation. SIDE EFFECTS Jaundice, headache, myalgia, pharyngitis, sinusitis. DRUG INTERACTION Pioglitazone is known to interact with other drugs like adrenaline, baclofen, budesonide, carbamazepine, clozapine, diazoxide, gemfibrozil, ginkgo biloba extract, ginseng extract, lovastatin, octreotide (Acetate), olanzapine, phenobarbitone, phenytoin (Na), rifabutin, risperidone, sotalol (HCl). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Pioglitazone acts as an agonist at peroxisome proliferator activated receptors (PPAR) in target tissues for insulin action such as adipose tissue, skeletal muscle, and liver. Activation of PPAR-gamma receptors increases the transcription of insulin-responsive genes involved in the control of glucose production, transport, and utilization. Pioglitazone both enhances tissue sensitivity to insulin and reduces hepatic gluconeogenesis.