CompositionThyroxine (12.5 mcg) SALT INFORMATIONThyroxine (12.5 mcg) TYPICAL USAGE Acquired hypothyroidism, Congenital hypothyroidism, Cretinism, Hypothyroidism, Myxedema coma, Non-toxic goiter. SIDE EFFECTS Sinus tachycardia, Diarrhoea, Tachycardia, Cardiac arrhythmias, Insomnia, Weight loss, Agitation, Tremors, Heat intolerance. DRUG INTERACTION Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially of: drugs that increase prolactin levels (e.g.,metoclopramide, methyldopa, phenothiazines such as prochlorperazine, antipsychotic medications such as haloperidol/olanzapine).This document does not contain all possible interactions. MECHANISM OF ACTION Levothyroxine sodium increases the basal metabolic rate (BMR) of carbohydrates, fats and proteins. It is also involved in the regulation and differentiation of cell growth. These effects are mediated at the cellular level by the thyroxine metabolite, tri-iodothyronine.