Tablets and Capsules

Vit E (400 Mg)

Availablity: In stock

MRP:Rs. 22.11 for 1 Strip(s) (10 Capsules each). This product is manufactured by Alidac Genetics & Pharmaceuticals

₹ 19.00

CompositionTocopherol Acetate (400 mg) SALT INFORMATIONTocopherol Acetate (400 mg) TYPICAL USAGE Cardiovascular disease, dementia, haemolytic anaemia, hepatotoxin poisoning, metal poisoning, vitamin deficiency, malignant neoplasms, muscular spasm, parkinsonism, prophylaxis and treatment of angina, retinopathy, surgery. SIDE EFFECTS Thrombosis, bleeding in vitamin K deficient patients, necrotizing enterocolitis in premature infants, flatulence, weakness, dizziness, fatigue, nausea, diarrhea, abdominal pain, blurred vision, thrombophlebitis, myopathy, hypertension. DRUG INTERACTION Tocopherol (Vitamin E) is known to interact with other drugs like colestipol (HCl), desogestrel, retinol (Vitamin A), vitamin K, warfarin (Na). Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required. MECHANISM OF ACTION Vitamin E's anti-atherogenic activity involves the inhibition of the oxidation of LDL and the accumulation of oxLDL in the arterial wall. It also appears to reduce oxLDL-induced apoptosis in human endothelial cells. Vitamin E inhibits protein kinase C (PKC) activity. The inhibition of PKC results in inhibition of smooth muscle cell proliferation, which is involved in atherogenesis. Vitamin E's antithrombotic and anticoagulant activities involves the downregulation of the expression of intracellular cell adhesion molecule(ICAM)-1 and vascular cell adhesion molecule(VCAM)-1 which lowers the adhesion of blood components to the endothelium. Vitamin E upregulates the expression of cytosolic phospholipase A2 and cyclooxygenase (COX)-1 which in turn enhances the release of prostacyclin. Prostacyclin is a vasodilating factor and inhibitor of platelet aggregation and platelet release. Vitamin E has also been found in culture to decrease plasma production of thrombin, a protein which binds to platelets and induces aggregation. A metabolite of vitamin E called vitamin E quinone or alpha-tocopheryl quinone (TQ) is a potent anticoagulant. This metabolite inhibits vitamin K-dependent carboxylase, which is a major enzyme in the coagulation cascade. Many disorders of the nervous system are caused by oxidative stress. Vitamin E protects against this stress, thereby protecting the nervouse system.

Product Specifications

Brand Alidac Genetics & Pharmaceuticals